SUMMATIVE ASSESSMENT IN A DOCTOR OF PHARMACY PROGRAM: A CRITICAL INSIGHT


Intracortical Causal Information Flow of Oscillatory Activity (Effective Connectivity) at the Sleep Onset Transition

We investigated the outlet sleep onset transition in humans from an effective connectivity perspective in a baseline condition (approx.16 h of wakefulness) and after sleep deprivation (40 h of sustained wakefulness).Using EEG recordings (27 derivations), source localization (LORETA) allowed us to reconstruct the underlying patterns of neuronal acti

read more


Josephin Domain Containing 2 (JOSD2) inhibition as Pan-KRAS-mutation-targeting strategy for colorectal cancer

Abstract KRAS is the most common mutated oncogenes in colorectal cancer (CRC), yet effective therapeutic strategies for targeting multiple KRAS mutations remained challenging.The prolonged protein stability of T-Shirt KRAS mutants contribute to their robust tumor-promoting effects, but the underlying mechanism is elusive.Herein by screening deubiqu

read more